PSA Doubling Time as a Predictive Factor on Repeat Biopsy for Detection of Prostate Cancer
نویسندگان
چکیده
منابع مشابه
PSA density as a better predictor of prostate cancer than percent-free PSA in a repeat biopsy.
BACKGROUND The aim of our study was to identify the optimal predictor of prostate cancer among several prostate-specific antigen (PSA) derivatives in repeat prostate biopsy. METHODS We retrospectively assessed the repeat prostate biopsy specimens, obtained between 1999 and 2008, of 212 patients with a total PSA (tPSA) of 4-10 ng/ml and normal digital rectal examination. Using a receiver opera...
متن کاملRecurrent PSA after prostatectomy for prostate cancer: implications of PSA doubling time.
After radical prostatectomy for prostate cancer, men frequently develop detectable levels of prostate specific antigen (PSA). A slow rate of increase, as characterized by the PSA doubling time (PSADT) is the principal marker for a favorable prognosis. Data and results presented in 2 recent clinical articles studying cohorts of men with clinical stage T1/T2 prostate cancer are reviewed and used ...
متن کاملA commentary on PSA velocity and doubling time for clinical decisions in prostate cancer.
Although the value of prostate-specific antigen (PSA) velocity or doubling time has never been seriously questioned for aiding the clinical management of recurrent or advanced cancer, there has historically been considerable uncertainty about PSA kinetics for decisions about biopsy and initial treatment. Recent studies, including analyses of cohorts from all the major randomized trials of local...
متن کاملDescribing Prostate Cancer Dynamics: Second Look at PSA-Doubling Time and PSA-Specific Growth Rate
Physicians responsible for patient care focus on readily available clinical and trending labo‐ ratory data to help direct the patient’s clinical course and evaluate efficacy of therapy. Most clinicians fail to incorporate newer parameters of tumor response such as tumor growth rate when evaluating patient treatment response. Available now, is a wealth of dynamic growth parameters that shed new ...
متن کاملA charting tool for estimating the PSA doubling time in patients with prostate cancer.
adjuvant chemotherapy and radiotherapy after breast-conserving surgery enhances late toxicities: Long-term results of the ARCOSEIN multicenter randomized study. Int J Radiat Oncol Biol Phys 2006;65:324–332. 2. Munshi A, Jalali R, Budrukar A. In regards to Arcangeli, et al. (Int J Radiat Oncol Biol Phys 2006;64:161–167). Int J Radiat Oncol Biol Phys 2006;65:632. 3. Arcangeli G, Pinnaro P, Rambon...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Japanese Journal of Clinical Oncology
سال: 2009
ISSN: 0368-2811,1465-3621
DOI: 10.1093/jjco/hyp091